Recently, Dr. David P. Labbé—from the RI-MUHC (Research Institute of the McGill University Health Centre)—explored what kind of molecular event takes place for prostate cancer to multiply faster and to be fatal when patients intake a high-fat diet. The study findings were published in the journal Nature Communications and stated that saturated fat consumption stimulates a cellular reprogramming that is linked with prostate cancer development and lethality. These observations can have clinical usefulness in recognizing patients who are at greater peril of more aggressive and lethal disease. Additionally, they hint that dietary involvement involving the lessening of animal fat, and particularly saturated fat intake in men having early-stage prostate cancer, can probably delay or diminish the menace of disease progression.
Some genes—or oncogenes—have a role in cancer initiation or development and MYC gene is one of those. Dr. Labbé said, “In this paper, we demonstrated that by imitating an MYC overexpression, the saturated fat consumption makes prostate cancer worse. MYC overexpression deeply rewires cellular programs and boosts an individual transcriptional sign. MYC is a major aspect in tumorigenesis, as it initiates malignant traits in normal cells and accelerates the development of cancer cells.”
On a similar note, recently, a study showed that body fat distribution is associated with a higher jeopardy of aggressive prostate cancer. In the first prospective research of directly assessed body fat distribution and prostate cancer peril, researchers discovered that greater levels of the thigh and abdominal fat are linked with an amplified peril of aggressive prostate cancer. The study was published in the journal Cancer and these findings can be helpful to a better understanding of the connection amid obesity and prostate cancer and present new insights for treatment. The past studies have demonstrated that obesity is linked with an increased risk of advanced prostate cancer and an inferior prognosis after diagnosis.
Jennifer Brooks opted to become a stringer and author due to her yearning interest towards language and questioning nature. She currently deals with the medical science and health realm at The BunBury Mail news platform. She dishes up her readers with an edifying article; be it associated to health or medical. Jennifer is known to be an extremely intellectual as well as an eye-catching personality when it comes to her health-related concern.